A trial of the efficacy, safety and impact on drug resistance of four drug regimens for seasonal intermittent preventive treatment for malaria in Senegalese children.

In the Sahel, most malaria deaths occur among children 1-4 years old during a short transmission season. A trial of seasonal intermittent preventive treatment (IPT) with sulfadoxine-pyrimethamine (SP) and a single dose of artesunate (AS) showed an 86% reduction in the incidence of malaria in Senegal...

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Main Authors: Cheikh Sokhna, Badara Cissé, El Hadj Bâ, Paul Milligan, Rachel Hallett, Colin Sutherland, Oumar Gaye, Denis Boulanger, Kirsten Simondon, François Simondon, Geoffrey Targett, Jo Lines, Brian Greenwood, Jean-François Trape
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2198946?pdf=render