Transcriptional analysis of antiviral small molecule therapeutics as agonists of the RLR pathway

The recognition of pathogen associated molecular patterns (PAMPs) by pattern recognition receptors (PRR) during viral infection initiates the induction of antiviral signaling pathways, including activation of the Interferon Regulator Factor 3 (IRF3). We identified small molecule compounds that activ...

Full description

Bibliographic Details
Main Authors: R.R. Green, C. Wilkins, S. Pattabhi, R. Dong, Y. Loo, M. Gale, Jr
Format: Article
Language:English
Published: Elsevier 2016-03-01
Series:Genomics Data
Online Access:http://www.sciencedirect.com/science/article/pii/S2213596016300204