Anti-Cancer Activity of As<sub>4</sub>O<sub>6</sub> and its Efficacy in a Series of Patient-Derived Xenografts for Human Cervical Cancer

Anti-Cancer Activity of As<sub>4</sub>O<sub>6</sub> and its Efficacy in a Series of Patient-Derived Xenografts for Human Cervical Cancer

Purpose: To investigate the anti-cancer effects of tetraarsenic hexoxide (TAO, As<sub>4</sub>O<sub>6</sub>) in cervical cancer cell lines and in a series of patient-derived xenograft (PDX) mouse models. Methods: Human cervical cancer cell lines, including HeLa, SiHa and CaSki...

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Bibliographic Details
Main Authors: Joseph J. Noh, Myeong-Seon Kim, Young-Jae Cho, Soo-Young Jeong, Yoo-Young Lee, Ji-Yoon Ryu, Jung-Joo Choi, Illju Bae, Zhaoyan Wu, Byoung-Gie Kim, Jae Ryoung Hwang, Jeong-Won Lee
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Pharmaceutics
Subjects:
cervical cancer
tetraarsenic hexoxide
patient-derived xenograft
autophagy
cisplatin
Online Access:https://www.mdpi.com/1999-4923/12/10/987

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https://www.mdpi.com/1999-4923/12/10/987

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