Inhibition of Autophagy Enhances the Antitumor Effect of Thioridazine in Acute Lymphoblastic Leukemia Cells

Inhibition of Autophagy Enhances the Antitumor Effect of Thioridazine in Acute Lymphoblastic Leukemia Cells

Acute lymphoblastic leukemia (ALL) is an aggressive malignant disorder of lymphoid progenitor cells that affects children and adults. Despite the high cure rates, drug resistance still remains a significant clinical problem, which stimulates the development of new therapeutic strategies and drugs to...

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Bibliographic Details
Main Authors: Carina Colturato-Kido, Rayssa M. Lopes, Hyllana C. D. Medeiros, Claudia A. Costa, Laura F. L. Prado-Souza, Letícia S. Ferraz, Tiago Rodrigues
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Life
Subjects:
acute lymphoblastic leukemia
apoptosis
autophagy
viability
thioridazine
Online Access:https://www.mdpi.com/2075-1729/11/4/365

Internet

https://www.mdpi.com/2075-1729/11/4/365

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