Fusarochromanone induces G1 cell cycle arrest and apoptosis in COS7 and HEK293 cells.

Fusarochromanone (FC101), a mycotoxin produced by the fungus Fusarium equiseti, is frequently observed in the contaminated grains and feedstuffs, which is toxic to animals and humans. However, the underlying molecular mechanism remains to be defined. In this study, we found that FC101 inhibited cell...

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Bibliographic Details
Main Authors: Ying Gu, Xin Chen, Chaowei Shang, Karnika Singh, Mansoureh Barzegar, Elahe Mahdavian, Brian A Salvatore, Shanxiang Jiang, Shile Huang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4226581?pdf=render