Long-Acting FGF21 Inhibits Retinal Vascular Leakage in In Vivo and In Vitro Models

Long-Acting FGF21 Inhibits Retinal Vascular Leakage in In Vivo and In Vitro Models

The aim of the current study was to investigate the impact of long-acting fibroblast growth factor 21 (FGF21) on retinal vascular leakage utilizing machine learning and to clarify the mechanism underlying the protection. To assess the effect on retinal vascular leakage, C57BL/6J mice were pre-treate...

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Bibliographic Details
Main Authors: Yohei Tomita, Zhongjie Fu, Zhongxiao Wang, Bertan Cakir, Steve S. Cho, William Britton, Ye Sun, Ann Hellström, Saswata Talukdar, Lois E.H. Smith
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:International Journal of Molecular Sciences
Subjects:
fibroblast growth factor 21 (fgf21)
tight junction
claudin-1
vascular endothelial growth factor (vegf)
vascular leakage
machine learning analysis
Online Access:https://www.mdpi.com/1422-0067/21/4/1188

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https://www.mdpi.com/1422-0067/21/4/1188

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