Mitochondrial transcription factor A plays opposite roles in the initiation and progression of colitis‐associated cancer

Mitochondrial transcription factor A plays opposite roles in the initiation and progression of colitis‐associated cancer

Abstract Background Mitochondria are key regulators in cell proliferation and apoptosis. Alterations in mitochondrial function are closely associated with inflammation and tumorigenesis. This study aimed to investigate whether mitochondrial transcription factor A (TFAM), a key regulator of mitochond...

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Bibliographic Details
Main Authors: Shirong Yang, Xianli He, Jing Zhao, Dalin Wang, Shanshan Guo, Tian Gao, Gang Wang, Chao Jin, Zeyu Yan, Nan Wang, Yongxing Wang, Yilin Zhao, Jinliang Xing, Qichao Huang
Format: Article
Language:English
Published: Wiley 2021-08-01
Series:Cancer Communications
Subjects:
colitis
colitis‐associated cancer
colorectal cancer
energy metabolism
inflammatory bowel diseases
intestinal homeostasis
Online Access:https://doi.org/10.1002/cac2.12184

Internet

https://doi.org/10.1002/cac2.12184

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