PACAP38 and PAC1 receptor blockade: a new target for headache?

PACAP38 and PAC1 receptor blockade: a new target for headache?

Abstract Pituitary adenylate cyclase activating polypeptide-38 (PACAP38) is a widely distributed neuropeptide involved in neuroprotection, neurodevelopment, nociception and inflammation. Moreover, PACAP38 is a potent inducer of migraine-like attacks, but the mechanism behind this has not been fully...

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Bibliographic Details
Main Authors: Eloisa Rubio-Beltrán, Edvige Correnti, Marie Deen, Katharina Kamm, Tim Kelderman, Laura Papetti, Simone Vigneri, Antoinette MaassenVanDenBrink, Lars Edvinsson, On behalf of the European Headache Federation School of Advanced Studies (EHF-SAS)
Format: Article
Language:English
Published: BMC 2018-08-01
Series:The Journal of Headache and Pain
Subjects:
PACAP
PAC1 receptor
Migraine
Prophylactic treatment
Online Access:http://link.springer.com/article/10.1186/s10194-018-0893-8

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http://link.springer.com/article/10.1186/s10194-018-0893-8

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