Comparison of amyloid PET measured in Centiloid units with neuropathological findings in Alzheimer’s disease

Comparison of amyloid PET measured in Centiloid units with neuropathological findings in Alzheimer’s disease

Abstract Background The Centiloid scale was developed to standardise the results of beta-amyloid (Aβ) PET. We aimed to determine the Centiloid unit (CL) thresholds for CERAD sparse and moderate-density neuritic plaques, Alzheimer’s disease neuropathologic change (ADNC) score of intermediate or high...

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Bibliographic Details
Main Authors: Sanka Amadoru, Vincent Doré, Catriona A. McLean, Fairlie Hinton, Claire E. Shepherd, Glenda M. Halliday, Cristian E. Leyton, Paul A. Yates, John R. Hodges, Colin L. Masters, Victor L. Villemagne, Christopher C. Rowe
Format: Article
Language:English
Published: BMC 2020-03-01
Series:Alzheimer’s Research & Therapy
Subjects:
Amyloid imaging
Alzheimer’s disease
Centiloids
Positron emission tomography
Neuropathology
Online Access:http://link.springer.com/article/10.1186/s13195-020-00587-5

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http://link.springer.com/article/10.1186/s13195-020-00587-5

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