Ultradeformable Archaeosomes for Needle Free Nanovaccination with Leishmania braziliensis Antigens.

Total antigens from Leishmania braziliensis promastigotes, solubilized with sodium cholate (dsLp), were formulated within ultradeformable nanovesicles (dsLp-ultradeformable archaeosomes, (dsLp-UDA), and dsLp-ultradeformable liposomes (dsLp-UDL)) and topically administered to Balb/c mice. Ultradeform...

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Bibliographic Details
Main Authors: Leticia H Higa, Laura Arnal, Mónica Vermeulen, Ana Paula Perez, Priscila Schilrreff, Cecilia Mundiña-Weilenmann, Osvaldo Yantorno, María Elena Vela, María José Morilla, Eder Lilia Romero
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4774928?pdf=render