Antioxidant-upregulated mesenchymal stem cells reduce inflammation and improve fatty liver disease in diet-induced obesity

Abstract Background The incidence of obesity and diabetes is increasing rapidly. Optimal management is still elusive. Obesity associated with type 2 diabetes is known to cause adipose tissue inflammation, increase oxidative stress, and cause white fat hyperplasia and mitochondrial dysfunction. In th...

Full description

Bibliographic Details
Main Authors: Cleyton C. Domingues, Nabanita Kundu, Yana Kropotova, Neeki Ahmadi, Sabyasachi Sen
Format: Article
Language:English
Published: BMC 2019-09-01
Series:Stem Cell Research & Therapy
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13287-019-1393-8