Berberine Improves Chemo-Sensitivity to Cisplatin by Enhancing Cell Apoptosis and Repressing PI3K/AKT/mTOR Signaling Pathway in Gastric Cancer

Berberine Improves Chemo-Sensitivity to Cisplatin by Enhancing Cell Apoptosis and Repressing PI3K/AKT/mTOR Signaling Pathway in Gastric Cancer

Gastric cancer is one of the most common malignancies ranks as the second leading cause of cancer-related mortality in the world. Cisplatin (DDP) is commonly used for gastric cancer treatment, whereas recurrence and metastasis are common because of intrinsic and acquired DDP-resistance. The aim of t...

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Bibliographic Details
Main Authors: Yingying Kou, Bending Tong, Weiqing Wu, Xiangqing Liao, Min Zhao
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Pharmacology
Subjects:
gastric cancer
cisplatin
berberine
apoptosis
PI3K/AKT/mTOR 2
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2020.616251/full

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https://www.frontiersin.org/articles/10.3389/fphar.2020.616251/full

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