Ibrutinib Could Suppress CA-125 in Ovarian Cancer: A Hypothesis

Ibrutinib is a small-molecule inhibitor of Bruton’s tyrosine kinase, an enzyme central in B cell development. It is indicated as a therapy for certain hematological diseases such as chronic lymphocytic leukemia (CLL), but also exerts off-target effects on several receptors and kinases. In this paper...

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Bibliographic Details
Main Authors: Julian Matthias Metzler, Daniel Fink, Patrick Imesch
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Applied Sciences
Subjects:
Btk
Online Access:https://www.mdpi.com/2076-3417/11/1/222