Diet- and Genetically-Induced Obesity Differentially Affect the Fecal Microbiome and Metabolome in Apc1638N Mice.

Diet- and Genetically-Induced Obesity Differentially Affect the Fecal Microbiome and Metabolome in Apc1638N Mice.

Obesity is a risk factor for colorectal cancer (CRC), and alterations in the colonic microbiome and metabolome may be mechanistically involved in this relationship. The relative contribution of diet and obesity per se are unclear. We compared the effect of diet- and genetically-induced obesity on th...

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Bibliographic Details
Main Authors: Anna C Pfalzer, Paula-Dene C Nesbeth, Laurence D Parnell, Lakshmanan K Iyer, Zhenhua Liu, Anne V Kane, C-Y Oliver Chen, Albert K Tai, Thomas A Bowman, Martin S Obin, Joel B Mason, Andrew S Greenberg, Sang-Woon Choi, Jacob Selhub, Ligi Paul, Jimmy W Crott
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4540493?pdf=render

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http://europepmc.org/articles/PMC4540493?pdf=render

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