Advanced targeted, cell and gene therapy approaches for pediatric hematological malignancies: results and future perspectives

Advanced targeted, cell and gene therapy approaches for pediatric hematological malignancies: results and future perspectives

Despite the survival of pediatric patients affected by hematological malignancies being improved in the last 20 years by chemotherapy and hematopoietic stem cell transplantation (HSCT), a significant amount of patients still relapses. Treatment intensification is limited by toxic side effects and is...

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Bibliographic Details
Main Authors: Chiara Francesca Magnani, Sarah eTettamanti, Francesca eMaltese, Nice eTurazzi, Andrea eBiondi, Ettore eBiagi
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-04-01
Series:Frontiers in Oncology
Subjects:
Gene Therapy
Adoptive immunotherapy
advanced therapy
pediatric leukemia
intelligent drugs
chimeric antigen receptor (CAR)
Online Access:http://journal.frontiersin.org/Journal/10.3389/fonc.2013.00106/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fonc.2013.00106/full

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