Prebiotic Route to Thymine from Formamide—A Combined Experimental–Theoretical Study

Prebiotic Route to Thymine from Formamide—A Combined Experimental–Theoretical Study

Synthesis of RNA nucleobases from formamide is one of the recurring topics of prebiotic chemistry research. Earlier reports suggest that thymine, the substitute for uracil in DNA, may also be synthesized from formamide in the presence of catalysts enabling conversion of formamide to formaldehyde. In...

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Bibliographic Details
Main Authors: Lukáš Petera, Klaudia Mrazikova, Lukas Nejdl, Kristyna Zemankova, Marketa Vaculovicova, Adam Pastorek, Svatopluk Civis, Petr Kubelik, Alan Heays, Giuseppe Cassone, Jiri Sponer, Martin Ferus, Judit Sponer
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Molecules
Subjects:
formamide
thymine
uracil
prebiotic chemistry
origin of life
Online Access:https://www.mdpi.com/1420-3049/26/8/2248

Internet

https://www.mdpi.com/1420-3049/26/8/2248

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