Progranulin deficiency causes the retinal ganglion cell loss during development

Abstract Astrocytes are glial cells that support and protect neurons in the central nervous systems including the retina. Retinal ganglion cells (RGCs) are in contact with the astrocytes and our earlier findings showed the reduction of the number of cells in the ganglion cell layer in adult progranu...

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Bibliographic Details
Main Authors: Yoshiki Kuse, Kazuhiro Tsuruma, Takahiro Mizoguchi, Masamitsu Shimazawa, Hideaki Hara
Format: Article
Language:English
Published: Nature Publishing Group 2017-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-01933-8