Loss of Claudin-3 Impairs Hepatic Metabolism, Biliary Barrier Function, and Cell Proliferation in the Murine LiverSummary

Loss of Claudin-3 Impairs Hepatic Metabolism, Biliary Barrier Function, and Cell Proliferation in the Murine LiverSummary

Background & Aims: Tight junctions in the liver are essential to maintain the blood-biliary barrier, however, the functional contribution of individual tight junction proteins to barrier and metabolic homeostasis remains largely unexplored. Here, we describe the cell type–specific expression...

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Bibliographic Details
Main Authors: Felix Alexander Baier, Daniel Sánchez-Taltavull, Tural Yarahmadov, Cristina Gómez Castellà, Fadi Jebbawi, Adrian Keogh, Riccardo Tombolini, Adolfo Odriozola, Mariana Castro Dias, Urban Deutsch, Mikio Furuse, Britta Engelhardt, Benoît Zuber, Alex Odermatt, Daniel Candinas, Deborah Stroka
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Cellular and Molecular Gastroenterology and Hepatology
Subjects:
Tight Junction
Bile Acid
Liver Regeneration
Claudin
Single-Cell RNA Sequencing
Online Access:http://www.sciencedirect.com/science/article/pii/S2352345X21000746

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http://www.sciencedirect.com/science/article/pii/S2352345X21000746

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