Detection of gut microbiota and pathogen produced N-acyl homoserine in host circulation and tissues

Abstract Recent studies suggest that quorum-sensing molecules may play a role in gut microbiota-host crosstalk. However, whether microbiota produces quorum-sensing molecules and whether those molecules can trans-kingdom transport to the host are still unknown. Here, we develop a UPLC-MS/MS-based ass...

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Bibliographic Details
Main Authors: Jingchuan Xue, Liang Chi, Pengcheng Tu, Yunjia Lai, Chih-Wei Liu, Hongyu Ru, Kun Lu
Format: Article
Language:English
Published: Nature Publishing Group 2021-06-01
Series:npj Biofilms and Microbiomes
Online Access:https://doi.org/10.1038/s41522-021-00224-5