Interfering with Tumor Hypoxia for Radiotherapy Optimization

Abstract Hypoxia in solid tumors is an important predictor of treatment resistance and poor clinical outcome. The significance of hypoxia in the development of resistance to radiotherapy has been recognized for decades and the search for hypoxia-targeting, radiosensitizing agents continues. This rev...

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Bibliographic Details
Main Authors: Irma Telarovic, Roland H. Wenger, Martin Pruschy
Format: Article
Language:English
Published: BMC 2021-06-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Online Access:https://doi.org/10.1186/s13046-021-02000-x