Detection of Mycobacterium leprae DNA from archaeological skeletal remains in Japan using whole genome amplification and polymerase chain reaction.

Detection of Mycobacterium leprae DNA from archaeological skeletal remains in Japan using whole genome amplification and polymerase chain reaction.

BACKGROUND: Identification of pathogen DNA from archaeological human remains is a powerful tool in demonstrating that the infectious disease existed in the past. However, it is very difficult to detect trace amounts of DNA remnants attached to the human skeleton, especially from those buried in a hu...

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Main Authors: Koichi Suzuki, Wataru Takigawa, Kazunari Tanigawa, Kazuaki Nakamura, Yuko Ishido, Akira Kawashima, Huhehasi Wu, Takeshi Akama, Mariko Sue, Aya Yoshihara, Shuichi Mori, Norihisa Ishii
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2928730?pdf=render

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http://europepmc.org/articles/PMC2928730?pdf=render

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