RefCell: multi-dimensional analysis of image-based high-throughput screens based on ‘typical cells’

RefCell: multi-dimensional analysis of image-based high-throughput screens based on ‘typical cells’

Abstract Background Image-based high-throughput screening (HTS) reveals a high level of heterogeneity in single cells and multiple cellular states may be observed within a single population. Currently available high-dimensional analysis methods are successful in characterizing cellular heterogeneity...

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Bibliographic Details
Main Authors: Yang Shen, Nard Kubben, Julián Candia, Alexandre V. Morozov, Tom Misteli, Wolfgang Losert
Format: Article
Language:English
Published: BMC 2018-11-01
Series:BMC Bioinformatics
Subjects:
Heterogeneity
Single-cell analysis
Image-based high-throughput screen
Online Access:http://link.springer.com/article/10.1186/s12859-018-2454-1

Internet

http://link.springer.com/article/10.1186/s12859-018-2454-1

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