PDX-1 Protein is Internalized by Lipid Raft-Dependent Macropinocytosis

PDX-1 Protein is Internalized by Lipid Raft-Dependent Macropinocytosis

PDX-1 plays a central role in regulating insulin gene transcription and differentiation of insulin-producing cells. It was previously reported that, due to its own Antennapedia-like protein transduction domain (PTD), exogenous PDX-1 protein can permeate cells and induces insulin gene expression in p...

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Main Authors: Hirofumi Noguchi M.D., Ph.D., Shinichi Matsumoto, Teru Okitsu, Yasuhiro Iwanaga, Yukihide Yonekawa, Hideo Nagata, Masayuki Matsushita, Fan-Yan Wei, Hideki Matsui, Kohtaro Minami, Susumu Seino, Yumi Masui, Shiroh Futaki, Koichi Tanaka
Format: Article
Language:English
Published: SAGE Publishing 2005-10-01
Series:Cell Transplantation
Online Access:https://doi.org/10.3727/000000005783982648

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https://doi.org/10.3727/000000005783982648

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