Runx2+ Niche Cells Maintain Incisor Mesenchymal Tissue Homeostasis through IGF Signaling

Runx2+ Niche Cells Maintain Incisor Mesenchymal Tissue Homeostasis through IGF Signaling

Summary: Stem cell niches provide a microenvironment to support the self-renewal and multi-lineage differentiation of stem cells. Cell-cell interactions within the niche are essential for maintaining tissue homeostasis. However, the niche cells supporting mesenchymal stem cells (MSCs) are largely un...

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Bibliographic Details
Main Authors: Shuo Chen, Junjun Jing, Yuan Yuan, Jifan Feng, Xia Han, Quan Wen, Thach-Vu Ho, Chelsea Lee, Yang Chai
Format: Article
Language:English
Published: Elsevier 2020-08-01
Series:Cell Reports
Subjects:
Runx2
mesenchymal stem cells
niche
transit-amplifying cells
adult mouse incisor
IGF signaling
Online Access:http://www.sciencedirect.com/science/article/pii/S221112472030992X

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http://www.sciencedirect.com/science/article/pii/S221112472030992X

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