Differential Alteration in Expression of Striatal GABAAR Subunits in Mouse Models of Huntington’s Disease

Differential Alteration in Expression of Striatal GABAAR Subunits in Mouse Models of Huntington’s Disease

Huntington’s disease (HD) is a neurodegenerative disorder characterized by progressive motor symptoms that are preceded by cognitive deficits and is considered as a disorder that primarily affects forebrain striatal neurons. To gain a better understanding of the molecular and cellular mechanisms ass...

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Bibliographic Details
Main Authors: Zhuowei Du, Margot Tertrais, Gilles Courtand, Thierry Leste-Lasserre, Laura Cardoit, Frédérique Masmejean, Christophe Halgand, Yoon H. Cho, Maurice Garret
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-06-01
Series:Frontiers in Molecular Neuroscience
Subjects:
Huntington’s disease
R6/1 mouse model
HdhQ111
striatum
GABAA receptor
synapse
Online Access:http://journal.frontiersin.org/article/10.3389/fnmol.2017.00198/full

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http://journal.frontiersin.org/article/10.3389/fnmol.2017.00198/full

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