Serum amyloid A induces NLRP-3-mediated IL-1β secretion in neutrophils.

Serum amyloid A induces NLRP-3-mediated IL-1β secretion in neutrophils.

Serum amyloid A (SAA) is an acute phase reactant with significant immunological activities, including effects on cytokine synthesis and neutrophil chemotaxis. Neutrophils can also release cytokines with proinflammatory properties. IL-1β is a key proinflammatory cytokine, the secretion of which is co...

Full description

Bibliographic Details
Main Authors: Kiyoshi Migita, Yasumori Izumi, Yuka Jiuchi, Hideko Kozuru, Chieko Kawahara, Minoru Nakamura, Tadashi Nakamura, Kazunaga Agematsu, Junya Masumoto, Michio Yasunami, Atsushi Kawakami, Katsumi Eguchi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4028190?pdf=render

Internet

http://europepmc.org/articles/PMC4028190?pdf=render

Similar Items