Upregulation of tumor necrosis factor-alpha in the anterior cingulate cortex contributes to neuropathic pain and pain-associated aversion

Injury associated pain involves subjective perception and emotional experience. The anterior cingulate cortex (ACC) is a key area involved in the affective component of pain processing. However, the neuroimmune mechanisms underlying enhanced ACC excitability following peripheral nerve injury are sti...

Full description

Bibliographic Details
Main Authors: Pei-Wen Yao, Shao-Kun Wang, Shao-Xia Chen, Wen-Jun Xin, Xian-Guo Liu, Ying Zang
Format: Article
Language:English
Published: Elsevier 2019-10-01
Series:Neurobiology of Disease
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996119301019