Factors affecting serum phenobarbital concentration changes in pediatric patients receiving elixir and powder formulations

Abstract Background Phenobarbital (PB) is commonly used as elixir and powder formulations in pediatric care. Its dose adjustment is performed based on individual drug concentration monitoring. Few studies have comprehensively analyzed the variation factors for serum PB concentration. In this study,...

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Bibliographic Details
Main Authors: Chihiro Shiraishi, Hiroko Matsuda, Toru Ogura, Takuya Iwamoto
Format: Article
Language:English
Published: BMC 2021-02-01
Series:Journal of Pharmaceutical Health Care and Sciences
Subjects:
Online Access:https://doi.org/10.1186/s40780-021-00190-2