Central angiotensin II stimulation promotes β amyloid production in Sprague Dawley rats.

BACKGROUND: Stress and various stress hormones, including catecholamines and glucocorticoids, have recently been implicated in the pathogenesis of Alzheimer's disease (AD), which represents the greatest unresolved medical challenge in neurology. Angiotensin receptor blockers have shown benefits...

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Bibliographic Details
Main Authors: Donglin Zhu, Jingping Shi, Yingdong Zhang, Bianrong Wang, Wei Liu, Zhicong Chen, Qiang Tong
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3030571?pdf=render