Host genetic factors affecting spontaneous HBsAg seroclearance in chronic hepatitis B patients.

Spontaneous clearance of hepatitis B surface antigen (HBsAg) in chronic hepatitis B (CHB) patients usually indicates a remission of hepatitis activity and a favorable outcome. Two single nucleotide polymorphisms (SNP), rs3077 near HLA-DPA1 region and rs9277535 near HLA-DPB1 region, have been shown t...

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Bibliographic Details
Main Authors: Huei-Ru Cheng, Chun-Jen Liu, Tai-Chung Tseng, Tung-Hung Su, Hwai-I Yang, Chien-Jen Chen, Jia-Horng Kao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3543438?pdf=render