Design and Validation of a Multiplex KIR and HLA Class I Genotyping Method Using Next Generation Sequencing

Design and Validation of a Multiplex KIR and HLA Class I Genotyping Method Using Next Generation Sequencing

Killer cell immunoglobulin-like receptors (KIR), considered the most polymorphic natural killer (NK) cell regulators, bind HLA class-I molecules or still unknown ligands. Interest in KIR genotyping is increasing because of the importance of these receptors for identifying the best possible donor in...

Full description

Bibliographic Details
Main Authors: Laia Closa, Francisco Vidal, Maria J. Herrero, Jose L. Caro
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-12-01
Series:Frontiers in Immunology
Subjects:
KIR
HLA
next generation sequencing
genotyping
NGS analysis
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.02991/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2018.02991/full

Similar Items