A Single-Cycle Influenza A Virus-Based SARS-CoV-2 Vaccine Elicits Potent Immune Responses in a Mouse Model

A Single-Cycle Influenza A Virus-Based SARS-CoV-2 Vaccine Elicits Potent Immune Responses in a Mouse Model

The use of virus-vectored platforms has increasingly gained attention in vaccine development as a means for delivering antigenic genes of interest into target hosts. Here, we describe a single-cycle influenza virus-based SARS-CoV-2 vaccine designated as scPR8-RBD-M2. The vaccine utilizes the chimeri...

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Bibliographic Details
Main Authors: Surapong Koonpaew, Challika Kaewborisuth, Kanjana Srisutthisamphan, Asawin Wanitchang, Theeradej Thaweerattanasinp, Janya Saenboonrueng, Sukontip Poonsuk, Juggragarn Jengarn, Ratchanont Viriyakitkosol, Jarin Kramyu, Anan Jongkaewwattana
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Vaccines
Subjects:
SARS-CoV-2
single-cycle influenza virus-based vaccine
spike RBD
spike-pseudotyped virus
Online Access:https://www.mdpi.com/2076-393X/9/8/850

Internet

https://www.mdpi.com/2076-393X/9/8/850

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