Rd9 is a naturally occurring mouse model of a common form of retinitis pigmentosa caused by mutations in RPGR-ORF15.

Rd9 is a naturally occurring mouse model of a common form of retinitis pigmentosa caused by mutations in RPGR-ORF15.

Animal models of human disease are an invaluable component of studies aimed at understanding disease pathogenesis and therapeutic possibilities. Mutations in the gene encoding retinitis pigmentosa GTPase regulator (RPGR) are the most common cause of X-linked retinitis pigmentosa (XLRP) and are estim...

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Bibliographic Details
Main Authors: Debra A Thompson, Naheed W Khan, Mohammad I Othman, Bo Chang, Lin Jia, Garrett Grahek, Zhijian Wu, Suja Hiriyanna, Jacob Nellissery, Tiansen Li, Hemant Khanna, Peter Colosi, Anand Swaroop, John R Heckenlively
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3341386?pdf=render

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http://europepmc.org/articles/PMC3341386?pdf=render

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