SK2 Channels Associate With mGlu1α Receptors and CaV2.1 Channels in Purkinje Cells

SK2 Channels Associate With mGlu1α Receptors and CaV2.1 Channels in Purkinje Cells

The small-conductance, Ca2+-activated K+ (SK) channel subtype SK2 regulates the spike rate and firing frequency, as well as Ca2+ transients in Purkinje cells (PCs). To understand the molecular basis by which SK2 channels mediate these functions, we analyzed the exact location and densities of SK2 ch...

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Bibliographic Details
Main Authors: Rafael Luján, Carolina Aguado, Francisco Ciruela, Xavier Morató Arus, Alejandro Martín-Belmonte, Rocío Alfaro-Ruiz, Jesús Martínez-Gómez, Luis de la Ossa, Masahiko Watanabe, John P. Adelman, Ryuichi Shigemoto, Yugo Fukazawa
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-09-01
Series:Frontiers in Cellular Neuroscience
Subjects:
cerebellum
potassium channel
mGlu receptor
electron microscopy
immunohistochemistry
calcium channel
Online Access:https://www.frontiersin.org/article/10.3389/fncel.2018.00311/full

Internet

https://www.frontiersin.org/article/10.3389/fncel.2018.00311/full

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