Cardamonin inhibits breast cancer growth by repressing HIF-1α-dependent metabolic reprogramming

Cardamonin inhibits breast cancer growth by repressing HIF-1α-dependent metabolic reprogramming

Abstract Background Cardamonin, a chalcone isolated from Alpiniae katsumadai, has anti-inflammatory and anti-tumor activities. However, the molecular mechanism by which cardamonin inhibits breast cancer progression largely remains to be determined. Methods CCK-8 and Hoechst 33258 staining were used...

Full description

Bibliographic Details
Main Authors: Jinmei Jin, Shuiping Qiu, Ping Wang, Xiaohui Liang, Fei Huang, Hui Wu, Beibei Zhang, Weidong Zhang, Xinhui Tian, Ren Xu, Hailian Shi, Xiaojun Wu
Format: Article
Language:English
Published: BMC 2019-08-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Cardamonin
Breast cancer
Mitochondrial oxidative phosphorylation
Reactive oxygen species
Apoptosis
Cell metabolism
Online Access:http://link.springer.com/article/10.1186/s13046-019-1351-4

Internet

http://link.springer.com/article/10.1186/s13046-019-1351-4

Similar Items