Inhibition of the alternative complement activation pathway in traumatic brain injury by a monoclonal anti-factor B antibody: a randomized placebo-controlled study in mice

Inhibition of the alternative complement activation pathway in traumatic brain injury by a monoclonal anti-factor B antibody: a randomized placebo-controlled study in mice

<p>Abstract</p> <p>Background</p> <p>The posttraumatic response to traumatic brain injury (TBI) is characterized, in part, by activation of the innate immune response, including the complement system. We have recently shown that mice devoid of a functional alternative p...

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Bibliographic Details
Main Authors: Holers V Michael, Ward Peter A, Rittirsch Daniel, Taha Mohy E, Hossini Amir M, Schmidt Oliver I, Thurman Joshua M, Harhausen Denise, Rozanski Michal, Leinhase Iris, Ertel Wolfgang, Stahel Philip F
Format: Article
Language:English
Published: BMC 2007-05-01
Series:Journal of Neuroinflammation
Online Access:http://www.jneuroinflammation.com/content/4/1/13

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http://www.jneuroinflammation.com/content/4/1/13

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