Genome-wide characterization of transcriptional patterns in high and low antibody responders to rubella vaccination.

Immune responses to current rubella vaccines demonstrate significant inter-individual variability. We performed mRNA-Seq profiling on PBMCs from high and low antibody responders to rubella vaccination to delineate transcriptional differences upon viral stimulation. Generalized linear models were use...

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Bibliographic Details
Main Authors: Iana H Haralambieva, Ann L Oberg, Inna G Ovsyannikova, Richard B Kennedy, Diane E Grill, Sumit Middha, Brian M Bot, Vivian W Wang, David I Smith, Robert M Jacobson, Gregory A Poland
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3641062?pdf=render