Antibody-mediated targeting of the transferrin receptor in cancer cells
Iron is essential for cell growth and is imported into cells in part through the action of transferrin (Tf), a protein that binds its receptor (TfR1 or CD71) on the surface of a cell, and then releases iron into endosomes. TfR1 is a single pass type-II transmembrane protein expressed at basal levels...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Permanyer
2016-11-01
|
| Series: | Boletín Médico del Hospital Infantil de México |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1665114616301320 |