Functional Modulation of Regulatory T Cells by IL-2.

The suppressive function of regulatory T cells (Tregs) is critical to the maintenance of immune homeostasis in vivo and yet, the specific identification of Tregs by phenotypic markers is not perfect. Tregs were originally identified in the CD4+CD25+ fraction of T cells, but FoxP3 expression was late...

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Bibliographic Details
Main Authors: Byung-In Moon, Tae Hun Kim, Ju-Young Seoh
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4631326?pdf=render