HERCing: Structural and Functional Relevance of the Large HERC Ubiquitin Ligases

HERCing: Structural and Functional Relevance of the Large HERC Ubiquitin Ligases

Homologous to the E6AP carboxyl terminus (HECT) and regulator of chromosome condensation 1 (RCC1)-like domain-containing proteins (HERCs) belong to the superfamily of ubiquitin ligases. HERC proteins are divided into two subfamilies, Large and Small HERCs. Despite their similarities in terms of both...

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Bibliographic Details
Main Authors: Jesús García-Cano, Arturo Martinez-Martinez, Joan Sala-Gaston, Leonardo Pedrazza, Jose Luis Rosa
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-08-01
Series:Frontiers in Physiology
Subjects:
ubiquitin
ligase
HERC
structure
function
cancer
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2019.01014/full

Internet

https://www.frontiersin.org/article/10.3389/fphys.2019.01014/full

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