Novel Phage Display-Derived Anti-Abrin Antibodies Confer Post-Exposure Protection against Abrin Intoxication

Novel Phage Display-Derived Anti-Abrin Antibodies Confer Post-Exposure Protection against Abrin Intoxication

Abrin toxin is a type 2 ribosome inactivating glycoprotein isolated from the seeds of Abrus precatorius (jequirity pea). Owing to its high toxicity, relative ease of purification and accessibility, it is considered a biological threat agent. To date, there is no effective post-exposure treatment for...

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Bibliographic Details
Main Authors: Adva Mechaly, Ron Alcalay, Tal Noy-Porat, Eyal Epstein, Yoav Gal, Ohad Mazor
Format: Article
Language:English
Published: MDPI AG 2018-02-01
Series:Toxins
Subjects:
abrin
monoclonal antibodies
phage-display
rabbit
recombinant antibodies
Online Access:http://www.mdpi.com/2072-6651/10/2/80

Internet

http://www.mdpi.com/2072-6651/10/2/80

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