Gene-expression analysis reveals that embryonic stem cells cultured under osteogenic conditions produce mineral non-specifically compared to marrow stromal cells or osteoblasts

Gene-expression analysis reveals that embryonic stem cells cultured under osteogenic conditions produce mineral non-specifically compared to marrow stromal cells or osteoblasts

Pluripotent cells, such as embryonic stem cells (ESCs), divide indefinitely and can differentiate to form mineralised nodules in response to osteogenic supplements. This suggests that they may be used as a cell source for bone replacement strategies. Here, we related the expression of osteogenic and...

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Bibliographic Details
Main Authors: ND Evans, RJ Swain, E Gentleman, MM Gentleman, MM Stevens
Format: Article
Language:English
Published: AO Research Institute Davos 2012-09-01
Series:European Cells & Materials
Subjects:
Bone
development
mineralisation
repair
stem cells
differentiation
osteogenesis
Online Access:http://www.ecmjournal.org/journal/papers/vol024/pdf/v024a15.pdf

Internet

http://www.ecmjournal.org/journal/papers/vol024/pdf/v024a15.pdf

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