Cerebrospinal fluid from patients with subarachnoid haemorrhage and vasospasm enhances endothelin contraction in rat cerebral arteries.

INTRODUCTION:Previous studies have suggested that cerebrospinal fluid from patients with subarachnoid hemorrhage (SAH) leads to pronounced vasoconstriction in isolated arteries. We hypothesized that only cerebrospinal fluid from SAH patients with vasospasm would produce an enhanced contractile respo...

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Main Authors: Barbara Assenzio, Erica L Martin, Edgaras Stankevicius, Federica Civiletti, Marco Fontanella, Riccardo Boccaletti, Maurizio Berardino, AnnaTeresa Mazzeo, Alessandro Ducati, Ulf Simonsen, Luciana Mascia
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4309584?pdf=render