An intronic variant in the GRP78, a stress-associated gene, improves prediction for liver cirrhosis in persistent HBV carriers.

An intronic variant in the GRP78, a stress-associated gene, improves prediction for liver cirrhosis in persistent HBV carriers.

BACKGROUND: Our previous study indicated that a common variant (rs430397 G>A) in the intron 5 of glucose-regulated protein 78 (GRP78) gene was associated with risk and prognosis of primary hepatocellular carcinoma (HCC), including HBV- and cirrhosis-related HCC. rs430397 polymorphism may be a con...

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Bibliographic Details
Main Authors: Xiao Zhu, Lianzhou Chen, Wenguo Fan, Marie C M Lin, Linwei Tian, Min Wang, Sheng Lin, Zifeng Wang, Jinfang Zhang, Jinlong Wang, Hong Yao, Hsiangfu Kung, Dongpei Li
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3136490?pdf=render

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http://europepmc.org/articles/PMC3136490?pdf=render

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