Correcting for 16S rRNA gene copy numbers in microbiome surveys remains an unsolved problem

Correcting for 16S rRNA gene copy numbers in microbiome surveys remains an unsolved problem

Abstract The 16S ribosomal RNA gene is the most widely used marker gene in microbial ecology. Counts of 16S sequence variants, often in PCR amplicons, are used to estimate proportions of bacterial and archaeal taxa in microbial communities. Because different organisms contain different 16S gene copy...

Full description

Bibliographic Details
Main Authors: Stilianos Louca, Michael Doebeli, Laura Wegener Parfrey
Format: Article
Language:English
Published: BMC 2018-02-01
Series:Microbiome
Subjects:
16S rRNA
Gene copy number
Microbiome surveys
Phylogenetic reconstruction
Online Access:http://link.springer.com/article/10.1186/s40168-018-0420-9

Internet

http://link.springer.com/article/10.1186/s40168-018-0420-9

Similar Items