EGF Induces Migration Independent of EMT or Invasion in A549 Lung Adenocarcinoma Cells

Tumors and the tumor microenvironment produce multiple growth factors that influence cancer cell behavior via various signal transduction pathways. Growth factors, like transforming growth factor β (TGFβ) and epidermal growth factor (EGF), have been shown to induce proliferation, migration, and inva...

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Bibliographic Details
Main Authors: Karin Schelch, Lisa Vogel, Anja Schneller, Jelena Brankovic, Thomas Mohr, Rupert L. Mayer, Astrid Slany, Christopher Gerner, Michael Grusch
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
EGF
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.634371/full