Deep sequencing of hepatitis B surface antigen gene in the preserved umbilical cords in immunoprophylaxis failure against mother-to-child HBV transmission

Deep sequencing of hepatitis B surface antigen gene in the preserved umbilical cords in immunoprophylaxis failure against mother-to-child HBV transmission

Abstract Background Vaccine escape mutants (VEMs) are one of the causes of breakthrough infections in the mother-to-child transmission of hepatitis B virus (HBV). We hypothesized that VEMs existing as minor populations in the maternal blood are associated with breakthrough infections in children. We...

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Bibliographic Details
Main Authors: Haruki Komatsu, Ayano Inui, Yasuto Suzuki, Masaya Sugiyama, Tomoo Fujisawa
Format: Article
Language:English
Published: BMC 2019-11-01
Series:BMC Infectious Diseases
Subjects:
Hepatitis B virus
Immunoprophylaxis
Umbilical cord
Nails
Mutant
Variant
Online Access:http://link.springer.com/article/10.1186/s12879-019-4624-9

Internet

http://link.springer.com/article/10.1186/s12879-019-4624-9

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