Human Retrovirus Codon Usage from tRNA Point of View: Therapeutic Insights

The purpose of this study was to investigate the balance between transfer ribonucleic acid (tRNA) supply and demand in retrovirus-infected cells, seeking the best targets for antiretroviral therapy based on the hypothetical tRNA Inhibition Therapy (TRIT). Codon usage and tRNA gene data were retrieve...

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Bibliographic Details
Main Authors: Diego Frias, Joana P. Monteiro-Cunha, Aline C. Mota-Miranda, Vagner S. Fonseca, Tulio De Oliveira, Bernardo Galvao-Castro, Luiz C. J. Alcantara
Format: Article
Language:English
Published: SAGE Publishing 2013-01-01
Series:Bioinformatics and Biology Insights
Online Access:https://doi.org/10.4137/BBI.S12093