Simvastatin Attenuates Abdominal Aortic Aneurysm Formation Favoured by Lack of Nrf2 Transcriptional Activity

Surgical intervention is currently the only option for an abdominal aortic aneurysm (AAA), preventing its rupture and sudden death of a patient. Therefore, it is crucial to determine the pathogenic mechanisms of this disease for the development of effective pharmacological therapies. Oxidative stres...

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Bibliographic Details
Main Authors: Aleksandra Kopacz, Ewa Werner, Anna Grochot-Przęczek, Damian Klóska, Karolina Hajduk, Christoph Neumayer, Alicja Józkowicz, Aleksandra Piechota-Polanczyk
Format: Article
Language:English
Published: Hindawi Limited 2020-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2020/6340190