Poly(3-hydroxybutyrate-CO-3-hydroxyvalerate) PHBHV biocompatible nanocarriers for 5-FU delivery targeting colorectal cancer

Poly(3-hydroxybutyrate-CO-3-hydroxyvalerate) PHBHV biocompatible nanocarriers for 5-FU delivery targeting colorectal cancer

Aiming to address the issue of poor bioavailability of most anti-tumor medicines against colorectal cancer, we developed a targeted anticancer nanocarrier using biocarriers able to both bind and easily release their load in a controlled manner. Poly(3-hydroxybutyrate-co-3-hydroxyvalerate) carriers w...

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Bibliographic Details
Main Authors: Ionut Cristian Radu, Ariana Hudita, Catalin Zaharia, Bianca Galateanu, Horia Iovu, Eugenia (Vasile) Tanasa, Sabina Georgiana Nitu, Octav Ginghina, Carolina Negrei, Aristidis Tsatsakis, Kelly Velonia, Mikhail Shtilman, Marieta Costache
Format: Article
Language:English
Published: Taylor & Francis Group 2019-01-01
Series:Drug Delivery
Subjects:
nanocarrier
5-fu
polyhydroxyalkanoate
ht-29
colorectal cancer
anticancer efficacy
Online Access:http://dx.doi.org/10.1080/10717544.2019.1582729

Internet

http://dx.doi.org/10.1080/10717544.2019.1582729

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